28 خرداد 1403
محسن صميمي

محسن صمیمی

مرتبه علمی: استادیار
نشانی: کرمانشاه، بزرگراه امام خمینی، دانشگاه صنعتی کرمانشاه
تحصیلات: دکترای تخصصی / مهندسی شیمی (بیوتکنولوژی)
تلفن: 08338305001
دانشکده: دانشکده مهندسی

مشخصات پژوهش

عنوان
A highly sensitive electrochemical biosensor for chlorpyrifos pesticide detection using the adsorbent nanomatrix contain the human serum albumin and the Pd:CdTe quantum dots
نوع پژوهش مقاله چاپ شده
کلیدواژه‌ها
Organophosphorus compounds, Chlorpyrifos, Pesticide, TGA-capped Pd:CdTe quantum dots, Human serum albumin, Faradic impedance spectroscopy
پژوهشگران حسنا احضاری (نفر اول)، میثم صفری (نفر دوم)، محسن صمیمی (نفر سوم)، مجتبی شمسی پور (نفر چهارم)، محمد باقر قلیوند (نفر پنجم)

چکیده

In the offered study, a biosensor using a novel nano-matrix consisted of the human serum albumin (HSA) and the Pd-doped CdTe quantum dots (Pd:CdTe) and sub-layer multiwall carbon nanotubes (MWCNT) was constructed. The biosensor was employed in rapid sensing of the chlorpyrifos (CPS) pesticide by a single frequency impedance (SFI) strategy. This biosensor response was based on the connections of the CPS to tryptophan residue located at position 214 of HSA content of matrix on the electrode. Biosensor response signals were recorded through impedance |Z| in different individual frequencies using the [Fe(CN)6]3−/4− probe as a connection index. The electron transfer resistance (Rct) of the biosensor was altered linearly by logarithm CPS concentration from 0.5 pM to 500 nM under the optimal conditions with a detection limit of 0.16 pM. The proposed presented biosensor exhibited high sensitivity, wide linear response, excellent reproducibility and stability. As a result, the proposed biosensor will be a promising candidate for screening trace amounts of CPS in the soil and water samples.