In this work, a comparison study was implemented on the pool boiling heat transfer coefficient (BHTC) between the copper sulfate and isopropanol solutions. To precise investigate; the bubble dynamic including departure diameter, departure frequency and active nucleation sites were examined. In addition, ultrasonic waves’ irradiation (25 kHz) was employed to intensive the solutions and improve the dynamic parameters due to cavitation phenomenon. First, although the cooper sulfate had a bigger bubble departure diameter and more active nucleation sites than isopropanole, its heat transef coefficient was lower due to great bubble departure frequency of isopropanol. Finally, Calus model with an average error of 12.8% for isopropanol and Palen with 13.1% for copper sulfate had the lowest errors. Moreover, the isoropanole at 20 V.% with 15% power of ultrasonic irradiation and the cooper sulfate at 10.5 V.% with 35% had the maximum increase in the BHTC as 10.549% and 18.238%, respectively.
