The force convection flow of non-Newtonian water/Carboxy-Methyl Cellulose (CMC)-CuO Nanofluid (NF) in three wavy channels and a straight channel was numerically investigated. The two dimensional governing equations were solved in the computational domain using the FLUENT software. The influence of Re and nanoparticle concentration (φ) on the pressure drop (ΔP), Nu, and global thermal and frictional entropy generation rates (S˙g,th and S˙g,f ) were studied for different Re and φ values. The results showed that the influence of Re on the Nu is much higher than that of φ. The increasing of the Re and decreasing of φ, results in increasing the Nu for four channels of the study. Besides, the sinusoidal channel has the highest Nu as compared to the other channels. Also, the highest pressure drop and total global entropy generation rate were obtained for the trapezoidal channel.
