In recent years, the use of supplementary cementing materials, especially in addition to concrete, has been the subject of many researches. Rice husk ash (RHA) is one of these materials that in this research, is added to the roller compacted concrete as one of the pozzolanic materials. This paper evaluates how different contents of RHA added to the roller compacted concrete pavement specimens, can influence on the strength and permeability. The results are compared to the control samples and determined optimal level of RHA replacement. As it was expected, RHA as supplementary cementitious materials, improved mechanical properties of roller compacted concrete pavement (RCCP). Also, the application of adaptive neuro-fuzzy inference system (ANFIS) in predicting the permeability and compressive strength is investigated. The obtained results shows that the predicted value by this model is in good agreement with the experimental, which shows the proposed ANFIS model is a useful, reliable, fast and cheap tool to predict the permeability and compressive strength. A mean relative error percentage (MRE %) less than 1.1% is obtained for the proposed ANFIS model. Also, the test results and performed modeling show that the optimal value for obtaining the maximum compressive strength and minimum permeability is offered by substituting 9% and 18% of the cement by RHA, respectively.